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What is the ApoB:ApoA1 ratio?

The ApoB:ApoA1 ratio is highly valuable for detecting atherogenic (plaque-filled artery) risk. The ApoB/ApoA1 ratio is stronger than the total cholesterol/HDL cholesterol and LDL/HDL cholesterol ratios in predicting risk. The lower the ApoB/ApoA1 ratio, the lower the risk. Learn more about ApoB and ApoA1.

How can I better understand my ApoB:ApoA1 ratio?

Several studies have defined certain ApoB:ApoA1 levels as markers for disease (ex. papers on metabolic syndrome, coronary artery disease, coronary heart disease, all-cause mortality, to list a few). The general consensus based on literature is that an optimal ApoB:ApoA1 ratio is < 0.8 to minimize the risk of disease onset.

Cleveland Heart Lab defines low-, moderate-, and high-risk values for adults as the following:

 Sex Low Risk Moderate Risk High Risk
Male < 0.77 0.77 – 0.95 > 0.95
Female < 0.63 0.63 – 0.78 > 0.78

How can I maintain an optimal ApoB:ApoA1 ratio?

If your ApoB:ApoA1 levels are high, you can try:

Dietary Changes: Following a Mediterranean or vegan diet, consuming more fermented dairy products, limiting sugar intake, and increasing protein intake can improve your ApoB:ApoA ratio. Additionally, incorporating more polyunsaturated fats (omega-3 and omega-6) and maintaining adequate vitamin D, vitamin C, and magnesium levels can help as well.

Lifestyle changes: Regular exercise and improving sleep hygiene may also alter unfavorable apolipoprotein profiles.

Where can I learn more?

DISCLAIMER: IF YOU ARE CONCERNED WITH ANY OF YOUR RESULTS, PLEASE CONSULT WITH YOUR PHYSICIAN.